Joe Hoye Dow ⚡️
Hey there 👋
I'm Joe Hoye Dow
Computational Biology / Bioinformatics
A Computational Biology PhD Candidate at Shanghai Jiao Tong University.
I’m currently working on ensemble conformational dynamics of Intrinsically Disordered Regions (IDRs) of proteins —— especially those transcription factors associated with the 3D genome —— by combining deep learning modeling and molecular dynamics simulations.
Let's connect!
Selected Projects
pyPaperFlow

pyPaperFlow
Paper reading

An automated literature processing platform for scientific researchers. Batch retrieve, fetch, parse, and structure papers from PubMed, arXiv, bioRxiv, ChemRxiv, and DOI-based sources. From paper retrieval to knowledge internalization, automate the heavy lifting and keep the judgment human.
Repowiki-cli

Repowiki-cli
GitHub coding

Query AI-generated documentation for any public GitHub repository — straight from your terminal. Including three wiki services: DeepWiki · Google Code Wiki · zread.ai.
Gromacs-Everything-Skill

Gromacs-Everything-Skill
Claude Code skill for Gromacs

Claude Code skill for Gromacs，designed for Molecular Dynamics Simulation Operation & QA.
Latest from blog

存在主义是一种人道主义
Life

本文节选自让 - 保罗・萨特《存在主义是一种人道主义》

Accurate structure prediction of biomolecular interactions with AlphaFold3
Paper

https://www.nature.com/articles/s41586-024-07487-w

Dynbench: 蛋白构象动力学研究, 构象集合效果好不等于动力学预测强
Code

dynbench: an oracle-calibrated benchmark for protein conformational dynamics (ensemble fidelity is not dynamical fidelity)